The Poem La Vénusalgie by Jean François Sacombe is a didactic and also an artistic source of reference for the specialists interested in the disease of syphilis and of its psychological implications. The degradation of body of those suffering from syphilis is also associated with a degenerescence of the psychic, which is recorded in numerous verses of the poem. In the hundreds of pages dedicated to the description, the pathology and therapy of this disease, the physician writer, by his talent, succeeds to give an esthetic connotation to the evil and the destructive effects of the contamination with the venereal scourge. The lancet and the pen are the favored instruments used by Sacombe, a surgeon and clinician and a writer of verse, making them symbols of the accuracy of his knowledge in the domain of medicine, and, at the same time, a proof of his passion for the artistic beauty.