One of the main medical objectives in case of alcohol dependence as well as of the study hereby is to obtain and maintain abstinence for a period as long as possible. The study focused on the benefits of the Hudolin systemic therapy (1) with the help of the Clubs together with the standard therapy in case of alcohol dependence. The indexes that were evaluated in the efficiency of the therapy are the following: abstinence, quality of life, as well as the compulsive wish to drink alcohol. The study was conceived in a prospective manner, with periodical evaluations, as the visits timing has as a main goal to register the patients’ shortterm and longterm evolution. The results showed that evaluated for a 12month period, the abstinence in case of patients under combined therapy was greater than in patients who received only standard therapy, the differences between the two groups being of statistical significance.