Background The clinical studies on the patients with depressive disorder proved a grown incidence of the alcohol dependence within the framework of this emotional pathology. Objective Establish the prevalence of depressive disorders in alcoholic patients before and after the detoxification phase. Method Our study is a descriptive one and included 158 patients, hospitalized for the first time because of alcohol addiction disorder and presenting depressive symptoms. Results After the treatment of the acute phase, a great number of patients still presented depressive symptoms and after the detoxification treatment, only a small percentage of the patients remained with depressive symptoms. Conclusions The therapeutical management of this comorbidity requires a strict evaluation of the severity of the depressive episode, the personalized approach of each pathological manifestation and the following in the dynamics of the depressive disorder associated with the dependence on the alcohol.