Alcohol consumption is often encountered as comorbidity in many cases initially submitted for other medical conditions, while also often representing the main etiological factor in those diseases determinism. In terms of psychiatric pathology, most of the have studies shown that nearly half of all patients with psychiatric disorders exhibit abusive consumption of alcohol. In this way,the etiopathogenic role of alcoholism can be often ascertained in most psychiatric disorders. Thus, the affective and anxiety disorders, the psychoses, dementias and personality disorders often include alcoholism as comorbidity. In addition, while some mental disorders are caused by abusive or long term consumption of alcohol, other appear due to withdrawal effects, and in other instances, the alcohol consumption aggravates a pre-existing psychiatric disorder. Thus, the present study was designed in order to determine the correlation between abusive consumption of alcohol and depression, as well as the autolytic ideation. Thus, the first objective was to determine the correlation between alcoholism and the level of depression as measured by The Hamilton Depression Scale (HAMD), through the comparison of patients with major depressive disorders without alcohol-related illnesses and patients with major depressive disorder and anxiety. Also,we were interested in determining the impact of alcoholism on suicidal ideation by comparing the presence of suicidal ideation in patients with major depression with and without alcohol-related comorbidity. In conclusion we demonstrated that the occurrence of alcoholism in patients with depression influence the level of depression measured by the HAMD Scale and also that there is an autolytic ideation in patients with depression influenced by the presence of alcohol consumption.